This module explores the structure-function relationship of various biomolecules, particularly proteins and DNA. The fundamentals covered include quaternary structures, non-covalent interactions in proteins and thermodynamics of protein folding. This module helps students appreciate the different structures of biomolecules, learn how the different structures of the biomolecules relate to their functions and learn the use of software to visualise the different biomolecules as well as their interactions with other molecules. This module also provides handson experience in protein crystallography and other techniques commonly used in structural biology.