A336 Biopharmaceutical Production

The development of high-value protein-based drugs like antibodies, growth factors and vaccines begins with upstream processes such as cell inoculation, bioreactor operation, and harvesting of cultures. Students will later be exposed to techniques in chromatography and tangential flow filtration required for the downstream processing of drugs. In this module, students will learn contamination control procedures and how to operate within a controlled clean room environment. Knowledge on Good Manufacturing Practice (cGMP) and Good Documentation Practice (GDP) will be applied throughout the module to reinforce the importance of product quality and safety in the biopharmaceutical industry. Concepts on using artificial intelligence for designing biologic modalities and running simulations for process optimisation will be briefly covered. Key aspects related to sustainability in the industry, such as carbon emissions, energy efficiency, and product life cycle management, will also be explored.