This module provides students with a sound understanding of the immune responses that underpin clinically important areas, namely defence against infections, hypersensitivity states and allergy, immunopathology, and transplantation. Students gain an overview of the innate and adaptive immunity. They learn to appreciate fundamental immunological events such as initiation of the immune response, leading from antigen presentation and co-stimulation through cell activation pathways to the actions of cytokines. The module also covers the building blocks of the immune system cells, organs and the major receptor molecules including antibodies, T cell receptors and MHC molecules. Furthermore, the module seeks to enhance students’ skills in experimental design, conducting simple immunology experiments and keeping of laboratory records.